Posts

Showing posts from February, 2023

A Comprehensive Comparison of Radial Arm Maze, Y Maze, and Water Maze for Memory Testing

  Introduction  : Radial arm maze, Y maze, and water maze are the three most commonly used methods for testing the spatial memory of rodents. All three methods have been used extensively in research, and each has its own advantages and disadvantages.   A radial arm maze is the easiest to set up and use, and it is the most sensitive to drugs that affect memory. However, it is also the least naturalistic of the three methods. Y maze  is more naturalistic than radial arm maze, but it is less sensitive to memory-impairing drugs. The water maze is the most naturalistic of the three methods, and it is the most sensitive to memory-impairing drugs. However, it is also the most difficult to set up and use.   The Radial Arm Maze   : The radial arm maze  is the most commonly used method for testing the spatial memory of rodents. It consists of a circular platform with nine radial arms extending outward from the center. The animal is placed at the center of the ma...

The Importance Of Elevated Plus Maze, Pelletizing Machine & Plethysmometer

Introduction  : The Elevated Plus Maze, Pelletizing Machine & Plethysmometer are three pieces of equipment that are essential for any research lab that is studying animal behavior. These pieces of equipment allow for the safe and accurate study of animals in a controlled environment.   The Elevated Plus Maze  is a type of apparatus that is used to study the anxiolytic and anticonvulsant properties of drugs. The maze consists of a series of raised platforms that the animal can walk on. The animal is placed on one platform and is then allowed to explore the maze.   The Pelletizing Machine is a type of device that is used to study the effect of drugs on the rate of food consumption. The machine is used to dispense food pellets to the animal at a set rate. The animal is then placed in a cage and is allowed to consume the pellets.   The Plethysmometer is a type of device that is used to measure the rate of blood flow. The device consists of a chamber that the ani...

The Fluid Bed Processor : A Comprehensive Guide

Introduction : A fluid bed processor is a type of machinery used in a variety of industries for a variety of purposes. In the most basic sense, a fluid bed processor is a machine that uses a fluid (usually air) to suspend and move particles of a solid material. Fluid bed processors can be used for a wide variety of tasks, including drying, granulating, coating, and mixing. They are commonly used in the pharmaceutical, food, and chemical industries. If you’re looking for a comprehensive guide to fluid bed processors, you’ve come to the right place! In this article, we’ll cover everything you need to know about fluid bed processors, including how they work, their applications, and their advantages and disadvantages. What is a Fluid Bed Processor ? A fluid bed processor  is a type of machinery used for various processes, such as drying, granulating, coating, and mixing. This machine utilizes a fluid, such as air, to suspend and move particles of a solid material. The machine has a num...

The Various Uses of a Ball Mill in the Pharmaceutical Industry

  Ball Mill In Pharmaceutics - The ball mill pharmaceutical  reduces the particle size of active ingredients and excipients. This process can improve the bioavailability of the drug, making it more effective. Ball mills can also be used to homogenize and blend active ingredients and excipients. This process can improve the uniformity of the final product. A ball mill is a type of grinder that is used to Grind, mix, and sometimes blend materials for use in the pharmaceutical industry. A ball mill consists of a ceramic or metal jar that is filled with grinding media (usually balls), which is then rotated to cause the balls to grind against each other. This action results in the grinding of the material into a powder. There are several different types of ball mills, each with its own advantages and disadvantages. The most common type of ball mill is the porcelain ball mill. These mills are constructed from high-quality porcelain and are very durable. They are also very effective ...

Use & features of Radial Arm Maze, Y Maze, And Plethysmometer

  Plethysmometer : An instrument known as a Plethysmometer  was developed specifically for measuring the swelling of rat or mouse paws precisely. The digital Plethysmometer is a very useful instrument for evaluating experimentally generated inflammatory responses in small mice and screening possible anti-inflammatory or anti-edema characteristics of medicinal drugs. The reflection of the water displacement from the animal paw's immersion in the measurement tubes into the second tube results in the volume displacement. The displacement volume is noted. By pushing the reset key between readings, the control unit can be reset to prevent inaccuracies caused by water adhering to an animal's paw. to prevent the mistake brought on by the animal's paw from becoming stuck with water. a foot switch that enables. The termination point of the measurement can be controlled quickly using hands-free experimentation.   Anti-inflammatory drugs are evaluated for their capacity to control e...

Process And Different Techniques of Tablet Coater, R&D Coater and Coating Tablet Machine

  Tablet Coater : Tablet covering  is a significant cycle step in tablet creation. The drug business needs arrangements that meet shading and taste-covering prerequisites. Tablet covering is the process in which a covering substance is put into the tablet's outer layer in order to get the appropriate dosage structure over the uncoated tablets. The advantages of cover are listed below. 1.  Improving the medication's flavor, aroma, and color 2.  Improving product stability 3.  Modifying release properties 4.  Enhancing the patient's ability to gulp with more ease 5.  To protect against the gastrointestinal climate 6.  To improve the mechanical resistance of the dosage form There are three principal processes for tablet covering: glossing coating, film coating, and enteric coating. Some of the different coating techniques - A coating is a covering that is applied to the surface of an object, sometimes referred to as the substrate. The coating may be ...

Function And Working Process Of Rapid Dryer And FBD Fluid Bed Dryer.

Image
  Rapid Dryer : A Rapid dryer   is   used for Drying sand samples for determining Moisture   percentage, Clay percentage, and Fineness number . Specification of Rapid Dryer - Sand is dried using a fast dryer. Hold onto the sample of sand. Don't move the tray from its rectangular spot. Adjust the temperature, and light intensity by using a regulator switch. Set drying time by timer. After elapsing the time drying will stop. A regulator, timer, and drying pan are components of a quick drier. There are three types of dryers - There are three main types of tumble dryers: heat pump tumble dryers, condenser tumble dryers, and vented tumble dryers. Function - Drying with the Fast Dryer takes use of the fluidized bed process, a technique similar to the one employed in large industrial dryers. Through a filter, outside air is sucked inside. The air is forced through the perforated plate and into the removable drying container by a blower after traveling through the engine and...

Working Principle & Process Of Ball Mill Machine In The Pharmaceutical Industry

  B all M ill Machine - A Ball Mill Machine     is excellent for combining dry and moist materials, as well as grinding crystalline material.   To grind or combine materials, a ball mill machine is typically used in mineral dressing operations as well as in paints, pyrotechnics, ceramics, and selective laser sintering.   Process of ball mill - Ball milling is a grinding method that grinds nanotubes into extremely fine powders. During the ball milling process, the collision between the tiny rigid balls in a concealed container will generate localized high pressure. Usually, ceramic, flint pebbles, and stainless steel are used.   Applications of ball mill - Ball mills are used to size-reduce down to or below 1 micron, including minerals, glass, advanced ceramics, metal oxides, semiconductor and solar cell materials, nutraceuticals, and medicines.   Advantages - 1.  It is suitable for milling toxic materials since it can be used in a completely enclo...