Use & features of Radial Arm Maze, Y Maze, And Plethysmometer

 Plethysmometer :

An instrument known as a Plethysmometer was developed specifically for measuring the swelling of rat or mouse paws precisely.

The digital Plethysmometer is a very useful instrument for evaluating experimentally generated inflammatory responses in small mice and screening possible anti-inflammatory or anti-edema characteristics of medicinal drugs. The reflection of the water displacement from the animal paw's immersion in the measurement tubes into the second tube results in the volume displacement. The displacement volume is noted. By pushing the reset key between readings, the control unit can be reset to prevent inaccuracies caused by water adhering to an animal's paw. to prevent the mistake brought on by the animal's paw from becoming stuck with water. a foot switch that enables. The termination point of the measurement can be controlled quickly using hands-free experimentation. 

Anti-inflammatory drugs are evaluated for their capacity to control epidemic conditions using the Plethysmometer (Paw Edema) test. The animal's paw is submerged in water that is kept in a special water cell during use, changing the resistance of the water cell as a result of the animal's immersion. 

Features –

1. No wetting agent is required.

2. One calibration/year.

3. By pressing a button, the auto-calibration mode makes calibration simple.

4. Controller with the line or battery power.

5. Software with password-protected experiment delete function.


Advantages -

1. delivering in-depth qualitative research, in particular, to increase the market for the term.

2. This in-depth examination of the Plethysmometer market will help  the market make more informed decisions, enabling you to develop more effective sector-specific business plans.

 

Radial Arm Maze : 

Olton and Samuelson created the Radial Arm Maze in 1976 to assess rats' capacity for spatial learning and memory.

The spatial learning and memory of small animals like rats and mice are assessed behaviorally using a procedure known as the radial arm maze (RAM). The RAM has a central platform with several arms projecting from it and is frequently made of acrylic material. 

A Radial Arm Maze has eight uniformly spaced "arms" that protrude from a central container. With a reward (usually food-based) at the far end that is concealed from view in the center compartment, each arm is an expanded column of equal length. 

During the test, the animal is often positioned on the middle platform and free to roam the maze. The animal's capacity for spatial learning and memory can be evaluated after tracking its movements using a variety of metrics, such as the number of arm entries, the length of time spent in each arm, and the number of errors committed.  By relocating the reward in the arms, the test can also be used to gauge working memory.

 

Y maze :

Because of a simple Y-shape design, Y Maze Rodents are offered a single choosing point with only two possibilities. commonly used to assess the preferences, spatial memory, and learning abilities of lab animals.

Rats and mice are capable of completing simple Y maze exercises. The mazes are perfect for use with any video-tracking system due to their non-reflective and odor-resistant structure. The walls, floor, and manual sliding doors of the mazes are all shades of grey.

Rats' and mice's spatial working memory is frequently tested using the Y maze, particularly for tasks that require spontaneous alternation.

The Panlab Y mazes can be connected to the SMART Video-Tracking Systems to track and analyze animal behavior and movements throughout the test.

Preclinical research typically employs the Y maze to assess behavioral tasks for assessing spatial learning and memory. Two common Y maze tests are spontaneous alternation testing and recognition memory tests. These tests have been shown to be sensitive to hippocampal damage, gene alterations, and amnestic drugs. Creative Biolabs employs these Y maze paradigms to evaluate the effects of experimental drugs on cognition or test mouse memory function.

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