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Showing posts from September, 2021

Fluidized Bed System

Full fluidization is guaranteed with the unique revolutionary swirl generating method which gives great uniformity of coverage and high returns to the end product. The major difficulty is how optimal and uniform granule covering may be achieved. All grains engaged in the process of coating should have the same coating thickness, irrespective of their size. In addition to handling aqueous as well as organic film coating systems, an advanced control panel helps you to monitor and record all the settings for the Fluid bed processor. The chamber generally is a vertical cylinder in a fluidized bed processor . A column of air that flows up from the lower center of the cylinders fluidizes the pellets. The tablets in the center travel upward and downwards through the chamber wall, from the base of the column into the air stream again. In the base and top of the chamber, there are spray nozzles used to insert the coating solution. The core of the pellet is fragile, abrasive, and tearing-p...

What is Film-coating on Tablets?

This is the most extensively used tablet coating technique in the pharmaceutical industry. It personifies the tablet with different dyes and helps to stabilize the chemical compound. The unpleasant smell and taste of the pill are also masked. The film coating technique includes placing film solutions on tablets through a sprayer. This procedure is done once with a polymer, plasticizer, solvent, and dye solution. The pills are sprayed and quickly dried in a rotating tablet pan. After drying, a thin coating of polymer is created around a tablet. The tablet can sometimes keep its color; however, this can be adjusted if the solution is mixed with various dyes. There are now numerous varieties of tablet coating machines on the market. The following are the three main categories. Standard Pan Perforated Pan Fluidized Bed Processor Film Coating Process A polymer is dissolved in a solvent as well as other materials such as plasticizers, dyes, ...

Hot Melt Extruder

The extruder is widely used for making pellets of different sizes starting from a minimum of 400 microns to a maximum of 2000 microns. Extruder gives mild compaction and is ideal for most pharmaceutical formulations related to palletization. The function of a spheronizer is to convert extrudes into spheroids. Spheronization is the necessary second step of granulation by extrusion – spheronization process where pharmaceutical products are made into small spheres or spheroids Activate the machine and load the pre-formulated wet mass into the feed funnel(Hopper). The material is forced through the extrusion chamber to cone mesh by axial force of Counter-rotating screws. Conical pressing roller forces the material through the perforations of Single cone mesh and the extrude formed. Hot Melt Extruder is a modification of screw extruders. A carefully controlled heater heats the barrel which conducts the heat to the product. The molten polymeric mass is extruded from the die plates. App...

Single Screw Extruder

The extruder is widely used for making pellets of different sizes starting from a minimum of 400 microns to a maximum of 2000 microns. Extruder gives mild compaction and is ideal for most pharmaceutical formulations related to palletization. The function of a spheronizer is to convert extrudes into spheroids. Spheronization is the necessary second step of granulation by extrusion – spheronization process where pharmaceutical products are made into small spheres or spheroids Activate the machine and load the pre-formulated wet mass into the feed funnel(Hopper). The material is forced through the extrusion chamber to cone mesh by axial force of Counter-rotating screws. Conical pressing roller forces the material through the perforations of Single cone mesh and the extrude formed. Application: Single Screw Extruder Machine is widely used for making pellets of different sizes starting from a minimum of 400 microns to a maximum of 2000 microns. Extruder gives mild compaction and is id...

Types of Tablet Coaters

  Tablet coating machines are used to cover the tablet surface with a thin film layer. The film is mostly used for: 1.       Hide the pill's color, flavor, and odor. 2.       Protection against physical or chemical damage to the drug. 3.       Regulate the medication's release. 4.       prevent the medicine from disintegration by digestive fluids. 5.       Enhance the tablet look - make the product more attractive. 6.       Include medicines or ingredients in the layer to prevent incompatibility with chemical products. Tablet coating machines operate on the basic premise of applying coating materials to a set of tablets in a bed that may move horizontally or vertically. A simultaneous airflow allows the solvent to evaporate. The coating is spread uniformly throughout the tablets by the bed's movement...